Erratum: Screening children with NF1 for optic pathway glioma –No
نویسندگان
چکیده
منابع مشابه
Functional outcome measures for NF1-associated optic pathway glioma clinical trials.
OBJECTIVE The goal of the Response Evaluation in Neurofibromatosis and Schwannomatosis Visual Outcomes Committee is to define the best functional outcome measures for future neurofibromatosis type 1 (NF1)-associated optic pathway glioma (OPG) clinical trials. METHODS The committee considered the components of vision, other ophthalmologic parameters affected by OPG, potential biomarkers of vis...
متن کاملOptic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity.
Whereas biallelic neurofibromatosis 1 (NF1) inactivation is observed in NF1-associated gliomas, astrocyte-restricted Nf1 conditional knockout mice do not develop gliomas. These observations suggest that NF1 glioma formation requires additional cellular or genetic conditions. To determine the effect of an Nf1 heterozygous brain environment on NF1 glioma formation, we generated Nf1+/- mice lackin...
متن کاملMortality in Children with Optic Pathway Glioma Treated with Up-Front BB-SFOP Chemotherapy
BACKGROUND In terms of overall survival (OS), limited data are available for the very long-term outcomes of children treated for optic pathway glioma (OPG) with up-front chemotherapy. Therefore, we undertook this study with the aim of clarifying long-term OS and causes of death in these patients. METHODS We initiated and analyzed a historical cohort study of 180 children with OPG treated in F...
متن کاملObsessive-compulsive disorder after therapy for an optic pathway glioma
a Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas b Department of Psychology, University of Houston–Clear Lake, Houston, Texas c Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas d Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houst...
متن کاملNon-optic glioma in adults and children with neurofibromatosis 1
BACKGROUND Non-optic gliomas occur in 5% of children with NF1, but little is known about these tumours in adults. We aimed to investigate progression, spontaneous regression and the natural history of non-optic gliomas in adults and compare these findings to the results found in children. RESULTS One thousand seven hundred twenty-two brain MRI scans of 562 unselected individuals with NF1 were...
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ژورنال
عنوان ژورنال: Eye
سال: 2010
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.2010.154